Enhancing Athletic Performance: Coluracetam Buyer’s Guide


Coluracetam is a unique nootropic within the racetam family that is both potent and fast-acting. It works by enhancing high-affinity choline uptake to increase levels of the neurotransmitter acetylcholine.

It underwent clinical trials for Alzheimer’s but failed to meet its objectives. Later, Brain Cells Inc conducted a phase 2a trial on major depression and anxiety with positive results but those trials were never published (1).

Improved Memory

Like piracetam, Buy coluracetam Europe improves memory by triggering the release of acetylcholine, a neurotransmitter involved in memory formation and recall. But it does this in a different way than most racetams, as it increases the high-affinity choline uptake (HACU) process. This makes neurons better able to convert choline into acetylcholine.

This allows the brain to form and store memories more effectively, as well as improve focus and wakefulness. It also helps with cognitive deficits associated with Alzheimer’s disease and other forms of dementia, by correcting imbalances in the brain’s chemistry and improving the activity of key neurotransmitters like dopamine and serotonin.

Coluracetam can protect the NMDA receptors against glutamate toxicity, thereby improving long-term potentiation (LTP), a key process for learning and memory formation. It has also been shown to improve AMPA potentiation, another process boosting cognitive function and alertness. It is believed to do this by helping the brain produce new neurons and boost neurogenesis. Unlike SSRIs, this drug does not affect serotonin levels so it can be taken alongside antidepressants without causing any adverse side effects.

Reduced Anxiety

Coluracetam, a new member of the racetam family, boosts high-affinity choline uptake and acetylcholine conversion. It is also an anxiolytic, improving mood and quieting anxiety. It can even help relieve the symptoms of schizophrenia because schizophrenics have hippocampal acetylcholine deficits (2).

Research suggests that it may affect AMPA receptors as well, enhancing long-term potentiation (LTP). LTP is essential to memory formation and storage (3).

Coluracetam is fat-soluble and best taken with a healthy fat source like Performance Lab(r) organic, non-GMO MCT Oil or a tablespoon of unrefined coconut oil. As with all supplements, start low and work your way up to a comfortable effect dose. For example, many first-time users feel fatigue after taking too high a dose, so it’s important to take this supplement in small increments until you find the dosage that works for you. A good stack combination is 5 to 10 mg of coluracetam with 750mg of aniracetam daily twice. This provides a nice energy boost and improves confidence and social fluency.

Enhanced Mood

Buy coluracetam is a fat-soluble nootropic that works to improve memory, learning, and focus. It also has mood enhancing properties that can increase confidence and motivation while soothing anxiety and depression symptoms.

It works by stimulating choline uptake in the brain which is converted into acetylcholine. This neurotransmitter is essential for memory formation, enhances focus, and helps with mental performance. It also modulates AMPA receptors which contribute to the improvement of mental health and mood.

Taking this nootropic with a choline source such as CDP-Choline or Alpha-GPC can help to boost the effects of this cognitive enhancer. This stack will also decrease the risk of possible side effects such as jitteriness or headaches.

Unlike some other cognitive enhancers, coluracetam is fast-acting. It peaks in the bloodstream about 30 minutes after ingestion and lasts for three to four hours. It is recommended to take it at the beginning of a day before you plan on doing a lot of rigorous mental work.

Better Focus

Like Noopept, coluracetam increases acetylcholine levels in the brain to improve memory. It also has antidepressant and anxiolytic properties. In fact, it is more effective than valium in improving anxiety in rats. However, more research needs to be done on human subjects before confirming these claims.

It also improves the function of cholinergic neurons in the brain by increasing the high affinity choline uptake (HACU) process. Unlike piracetam, it does not make ACh receptors more sensitive to acetylcholine, but rather by enhancing the synthesis of acetylcholine from choline.

It is recommended to take it with a fat-soluble choline source such as Alpha GPC or a tablespoon of unrefined coconut oil for better absorption into your brain cells. Additionally, because of its cholinergic effects, it can counteract the effect of any medications you may be taking that have an anticholinergic effect. This includes some antipsychotics, Parkinson’s medications and Benadryl. You should also avoid caffeine while taking it as it can interfere with the HACU process and lead to tolerance build-up.

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